SCOTTSDALE, Ariz. -- Jonathan Herrera's two-run double and Chris Nelson's opportunistic baserunning in a four-run sixth inning lifted the Rockies to a 9-8 come-from-behind victory over the Mariners at Salt River Fields at Talking Stick on Tuesday afternoon.

Nelson scored the go-ahead run from third when he alertly headed home on pitcher Charlie Furbush's pickoff throw to first.

Carlos Peguero's two-run homer highlighted a five-run fifth inning as the Mariners overcame an early deficit to take an 8-5 lead, before the Rockies rallied with their four-run sixth.

The teams will meet again at Salt River Fields on Wednesday to finish their Cactus League schedules. The Mariners opened the regular season in Tokyo, Japan, last week, splitting two games with the Athletics, and will resume the regular season at Oakland on Friday. The Rockies will open at Houston on Friday night.

The Rockies entered the fifth with a 5-1 lead, but the Mariners' Kyle Seager and Michael Saunders doubled, and Alex Liddi singled to chase Rockies starter Juan Nicasio with one out. Nicasio was charged with four runs and eight hits in 4 1/3 innings, and an encouraging comeback from a broken neck he suffered last year ended with a 3.90 spring ERA.

Nicasio said he could not control the movement of his fastball.

"I'd throw it in the middle and it would go to the side; I couldn't throw strikes," Nicasio said. "My best pitch is the fastball."

Rockies right-hander Tyler Chatwood gave up Peguero's homer, his fifth of the spring, to tie the score at 5-5. Chatwood later gave up a Casper Wells single and a triple to Munenori Kawasaki - a Japanese free agent who earned a spot as a utility player -- that gave the Mariners a 6-5 lead.

Kyle Seager led off the Mariners' sixth with a triple off Chatwood. Miguel Olivo singled home Seager, then Peguero, who had three hits, singled home Olivo for an 8-5 lead.

Todd Helton knocked an RBI single in a two-run first inning against Mariners starter Erasmo Ramirez, a 21-year-old rookie who is in position to make the club when the Mariners' regular season resumes. Michael Cuddyer's leadoff double and Jason Giambi's run-scoring single highlighted the three-run fourth inning against Mariners reliever Tom Wilhelmsen.

The Mariners ran the game with relievers to keep the starting staff fresh.

Rockies up next: Right-hander Jhoulys Chacin, who will start Monday's home opener against the Giants, will start the Rockies' final Cactus League game, against the Mariners at Salt River Fields at Talking Stick. Also, Rockies shortstop Troy Tulowitzki, out since being hit by a pitch from Indians pitcher Ubaldo Jimenez on Sunday, expects to return to the Rockies' lineup.